Endocrine Abstracts

Turner’s syndrome is one of the most common chromosomal abnormalities affecting 1 in 2500 live births. Short stature and gonadal dysgenesis are known as the hallmarks of the syndrome since Henry Turner described the original cases in the late 1930s. Although the majority of these patients have streak ovaries as a result of stromal fibrosis, the uterus is intact, albeit with atrophic endometrium due to the hypoestrogenic state. We report a case of ...

A 68-year-old lady presented to the medical assessment unit with history of muscle cramps involving both hands and legs of 5 days duration. She also gave a history of diarrhoea of 2 weeks duration. Her background medical history includes hypertension, hypercholesterolemia and dyspepsia for which she was taking Irbesartan/hydrochlorothiazide combination tablets, simvastatin and omeprazole.General physical examination revealed positive Chovstek’s and ...

Case history: An 84-year old man with known non-functioning pituitary macroadenoma was admitted with productive cough and headache. Clinical assessment revealed evidence of pneumonia and antibiotic treatment was initiated. However subsequently the patient’s GCS dropped to 12. Left-sided 6th nerve palsy was present, but patient drowsiness precluded visual-field examination. CT brain showed pituitary tumour apoplexy due to haemorrhage, confirmed on MRI. His condi...

Background: Hyperadrogenemia is one of the most commonly encountered endocrine disorders in reproductive-aged women. By far the most common causes of androgen excess are functional which account for more than 90% of cases. Androgen and ovarian tumours producing excess androgen are however very rare and only account for about 0.2% of cases.Case history: A 62-year-old lady admitted to hospital with pneumonia was found to have an ill defined, firm, non-tend...

Bariatric surgery in people with morbid obesity results in effective long-term weight loss, and resolution or reduction in the severity of several co-morbid conditions. The majority of obese people with type 2 diabetes who undergo bariatric surgery, achieve remission of their diabetes or a significant reduction of their glucose lowering therapy in the long-term. We conducted a retrospective observational study to assess changes in body weight and glycaemic control in obese typ...